Joe Hart will return in place of Costel Pantilimon, whilst Vincent Kompany is expected to have recovered from his calf strain and should partner Matija Nastasic in the heart of defence. After sitting out the comfortable FA Cup victory over Leeds, Gael Clichy is likely to start ahead of Aleks Kolarov.
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Further forward, Gareth Barry could replace Javi Garcia if he has recovered from his injury, although the option is there for Roberto Mancini to name both, with Yaya Toure is his more advanced role. James Milner should keep Samir Nasri out of the side, whilst Carlos Tevez has an exellent record against Chelsea and looks set to continue alongside Sergio Aguero.
Here is the side Mancini could select:
Referee: Andre Marriner
Prediction: MAN CITY 2 – 1 Chelsea: It should be a tight affair, with two very good teams who are not quite at their best. Goals to be scored by Sergio Aguero, Carlos Tevez and Juan Mata.
William Hill have some excellent odds for this match: Matija Nastasic is a startling 41/1 to score the first goal whilst Sergio Aguero to score first and City to win 2-1 is also tempting at 41/1. Bet here now!